Open AccessSusceptibility of anaerobic bacteria to BAY v 3522
Author(s) -
Carl Erik Nord,
Margareta Rylander,
S. Ragnar Norrby
Publication year - 1991
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.35.3.594
Subject(s) - cefoxitin , clindamycin , cefadroxil , amoxicillin , metronidazole , agar dilution , anaerobic bacteria , cefuroxime , antibiotics , microbiology and biotechnology , anaerobic exercise , bay , nitroimidazole , antibacterial agent , medicine , doxycycline , bacteria , chemistry , biology , cephalosporin , staphylococcus aureus , minimum inhibitory concentration , physiology , civil engineering , engineering , genetics , pathology
The activity of BAY v 3522 against 340 strains of anaerobic bacteria was determined by an agar dilution method. Its activity was compared with those of amoxicillin, amoxicillin-clavulanate, cefaclor, cefadroxil, cefoxitin, cefuroxime, cephalexin, clindamycin, doxycycline, and metronidazole. BAY v 3522, amoxicillin-clavulanate, cefoxitin, clindamycin, and metronidazole were the most active agents tested. On the basis of these results, BAY v 3522 appears to have an antibacterial activity that warrants further investigation in clinical trials.