Open AccessDamage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271
Author(s) -
João Paulo Cabral
Publication year - 1991
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.35.2.341
Subject(s) - pseudomonas syringae , cytoplasm , pseudomonas aeruginosa , programmed cell death , pseudomonadaceae , pseudomonas , microbiology and biotechnology , cell membrane , cell , fungicide , pseudomonadales , biology , membrane , chemistry , bacteria , biochemistry , apoptosis , botany , pathogen , genetics
Treatment of Pseudomonas syringae cells with low concentrations of the fungicide dodecylguanidine monoacetate (dodine) resulted in cell death and leakage of K+, UV-absorbing materials, and ribose-containing molecules. The results suggest that dodine causes gross and extensive damage to the cytoplasmic membrane, which is probably implicated in the death of cells.