Open AccessActivity of meropenem against antibiotic-resistant or infrequently encountered gram-negative bacilli
Author(s) -
James H. Jorgensen,
Louise Maher,
A W Howell
Publication year - 1991
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.35.11.2410
Subject(s) - meropenem , microbiology and biotechnology , imipenem , morganella morganii , providencia , gentamicin , aeromonas , ciprofloxacin , enterobacter , cefotaxime , antibiotics , biology , klebsiella , enterobacteriaceae , bacilli , ceftazidime , pseudomonas aeruginosa , antibiotic resistance , bacteria , escherichia coli , biochemistry , genetics , gene
Meropenem was compared in vitro with imipenem as well as with several other contemporary beta-lactams, ciprofloxacin, and gentamicin against a group of highly antibiotic resistant members of the family Enterobacteriaceae and a collection of oxidase-positive and/or glucose-nonfermentative gram-negative bacilli. In this study, meropenem was more active than imipenem against isolates of Enterobacter, Klebsiella, Morganella, Providencia, Alcaligenes, Aeromonas, and Pasteurella.