Open AccessAntimicrobial properties of N-carboxybutyl chitosan
Author(s) -
Riccardo A.A. Müzzarelli,
R. Tarsi,
Oscar Filippini,
Eleonora Giovanetti,
G. Biagini,
Pietro E. Varaldo
Publication year - 1990
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.34.10.2019
Subject(s) - chitosan , chitin , antimicrobial , microbiology and biotechnology , minimum inhibitory concentration , chemistry , biology , biochemistry
N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.