Open AccessTrimethoprim resistance in Escherichia coli isolates from a geriatric unit
Author(s) -
Elli Heikkilä,
Lars Sundström,
Pentti Huovinen
Publication year - 1990
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.34.10.2013
Subject(s) - escherichia coli , trimethoprim , dihydrofolate reductase , microbiology and biotechnology , biology , sulfamethoxazole , enterobacteriaceae , urine , antibiotics , gene , genetics , biochemistry
The frequency of trimethoprim resistance among Escherichia coli isolates from urine samples collected at Turku City Hospital, Turku, Finland, remained at 40% during 1984 to 1988. The proportion of highly resistant (MIC, greater than or equal to 1,024 micrograms/ml) isolates increased, however, and most of these harbored the type I dihydrofolate reductase gene. Only a few isolates possessed type II or VII genes.