Open AccessActivities of five new fluoroquinolones against Pseudomonas pseudomallei
Author(s) -
Mark Winton,
E. Dale Everett,
Stephen Dolan
Publication year - 1988
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.32.6.928
Subject(s) - norfloxacin , ofloxacin , ciprofloxacin , enoxacin , broth microdilution , microbiology and biotechnology , melioidosis , burkholderia pseudomallei , antibacterial agent , pseudomonas , pefloxacin , biology , antibiotics , minimum inhibitory concentration , bacteria , genetics
Thirty-four isolates of Pseudomonas pseudomallei were tested by a broth microdilution technique for susceptibility to amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin. Ciprofloxacin was the most active agent tested, with an MIC for 90% of the strains tested of 8 micrograms/ml. These in vitro results suggest that the fluoroquinolones tested would not be optimal for therapy of melioidosis.