In vitro susceptibilities of common pediatric pathogens to LY163892 | Zendy

S Shelton | Zendy; John D. Nelson | Zendy

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In vitro susceptibilities of common pediatric pathogens to LY163892

Author(s) -

S Shelton,

John D. Nelson

Publication year - 1988

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.32.2.268

Subject(s) - cefaclor , amoxicillin , clavulanic acid , haemophilus influenzae , microbiology and biotechnology , moraxella (branhamella) catarrhalis , antibacterial agent , antibiotics , cephalosporin , beta lactamase , moraxella catarrhalis , escherichia coli , chemistry , medicine , biology , biochemistry , gene

LY163892 is a carbacephem antibiotic for oral administration with an antibacterial spectrum similar to that of cefaclor and amoxicillin-clavulanic acid. It has greater stability than cefaclor and greater activity against beta-lactamase-producing Haemophilus influenzae and Escherichia coli. LY163892 is less active than amoxicillin against streptococci and less active than amoxicillin-clavulanic acid against Branhamella catarrhalis but comparable against other pathogens.

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