Open AccessIn vitro activity of zinc salts against human rhinoviruses
Author(s) -
Felix Geist,
J A Bateman,
Frederick G. Hayden
Publication year - 1987
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.31.4.622
Subject(s) - rhinovirus , zinc , in vitro , common cold , cytopathic effect , chemistry , microbiology and biotechnology , biological activity , cell culture , pharmacology , biochemistry , virology , biology , immunology , virus , organic chemistry , genetics
The antiviral activity of zinc salts against rhinovirus types 1A and 39 was assayed by yield reduction and inhibition of cytopathic effect in cell culture. The findings indicate that the zinc salts tested have low in vitro therapeutic indices and suggest that the possible beneficial effects of zinc lozenges in reducing cold symptoms may not be related to selective antirhinovirus activity.