In vitro activity of zinc salts against human rhinoviruses | Zendy

Felix Geist | Zendy; J A Bateman | Zendy; Frederick G. Hayden | Zendy

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In vitro activity of zinc salts against human rhinoviruses

Author(s) -

Felix Geist,

J A Bateman,

Frederick G. Hayden

Publication year - 1987

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.31.4.622

Subject(s) - rhinovirus , zinc , cytopathic effect , in vitro , common cold , microbiology and biotechnology , chemistry , cell culture , biological activity , virology , pharmacology , biochemistry , biology , virus , immunology , organic chemistry , genetics

The antiviral activity of zinc salts against rhinovirus types 1A and 39 was assayed by yield reduction and inhibition of cytopathic effect in cell culture. The findings indicate that the zinc salts tested have low in vitro therapeutic indices and suggest that the possible beneficial effects of zinc lozenges in reducing cold symptoms may not be related to selective antirhinovirus activity.

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