Open AccessComparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae
Author(s) -
J. H. Jorgensen,
J S Redding,
A W Howell
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.29.6.1090
Subject(s) - cefaclor , haemophilus influenzae , cephalosporin , amoxicillin , microbiology and biotechnology , antibiotics , antibacterial agent , clavulanic acid , beta lactamase , minimum inhibitory concentration , chemistry , medicine , biology , escherichia coli , biochemistry , gene
LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.