Comparative activities of LY 164846 and other orally administered beta-lactam antibiotics against Haemophilus influenzae
Author(s) -
J. H. Jorgensen,
J S Redding,
A W Howell
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.29.6.1090
Subject(s) - cefaclor , haemophilus influenzae , cephalosporin , amoxicillin , microbiology and biotechnology , antibiotics , antibacterial agent , clavulanic acid , beta lactamase , minimum inhibitory concentration , chemistry , medicine , biology , escherichia coli , biochemistry , gene
LY 164846, a new oral cephalosporin, demonstrated very good inhibitory and bactericidal activities against Haemophilus influenzae irrespective of the production of beta-lactamase by the test strains. However, its activity was not markedly superior to that of either Augmentin (amoxicillin plus clavulanate) or cefaclor.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom