Open AccessProperties of a novel carbenicillin-hydrolyzing beta-lactamase (CARB-4) specified by an IncP-2 plasmid from Pseudomonas aeruginosa
Author(s) -
A. Philippon,
G. Paul,
A Thabaut,
George A. Jacoby
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.29.3.519
Subject(s) - carbenicillin , pseudomonas aeruginosa , plasmid , microbiology and biotechnology , isoelectric point , chemistry , beta lactamase , biology , bacteria , escherichia coli , enzyme , biochemistry , genetics , gene
CARB-4, a novel carbenicillin-hydrolyzing beta-lactamase with an isoelectric point of 4.3, was discovered in a strain of Pseudomonas aeruginosa from France. It was determined by a multiresistant transmissible plasmid belonging to the P-2 incompatibility group.