Open AccessIn vitro antimicrobial susceptibility of a Mycobacterium sp. isolated from patients with Crohn's disease
Author(s) -
Rodrick J. Chiodini,
Herbert J. Van Kruiningen,
Walter R. Thayer,
J A Coutu,
R. S. Merkal
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.26.6.930
Subject(s) - capreomycin , microbiology and biotechnology , clofazimine , antimicrobial , carbenicillin , ethionamide , ethambutol , streptomycin , biology , antibiotics , ampicillin , immunology , leprosy
The in vitro susceptibility of three strains of an unclassified Mycobacterium sp., isolated from three patients with Crohn's disease, to 23 antimicrobial agents was determined by a modified broth dilution method with 7H9 broth containing oleic acid-albumin-dextrose-catalase, Tween 80, and mycobactin J. All three strains were susceptible to streptomycin, viomycin, rifampin, clofazimine, cefazolin, amikacin, and kanamycin and resistant to p-aminosalicylic acid, cycloserine, 2-thiophenecarboxylic acid hydrazide, trimethoprim, diaminodiphenylsulfone, sulfamethoxazole, sulfadimethoxine, polymyxin B, metronidazole, neomycin, and carbenicillin. Variable results between strains were encountered with ethambutol, ethionamide, capreomycin, amoxicillin, and cephalothin.