Open AccessTreatment of typhoid fever with cefamandole
Author(s) -
Marwan Uwaydah,
Nabil T. Nassar,
Hani Harakeh,
Shahe Vartivarian,
Akram Talhouk,
Hagop Kantarjian
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.26.3.426
Subject(s) - cefamandole , typhoid fever , medicine , antibiotics , cephalosporin , antibiotic therapy , surgery , microbiology and biotechnology , virology , biology
Cefamandole therapy was evaluated in nine patients with typhoid fever. Six patients, including all five who received the antibiotic by continuous intravenous drip (8.0 g daily), were cured. Dosage schedules resulting in maintenance of antibiotic concentrations in serum high above the MIC seemed to correlate well with treatment success.