Open AccessComparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species
Author(s) -
Kenneth E. Aldridge,
Charles V. Sanders,
A Janney,
Sebastian Faro,
Robert Marier
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.26.3.410
Subject(s) - mezlocillin , cefoxitin , ceftizoxime , cefotetan , bacteroides fragilis , azlocillin , microbiology and biotechnology , penicillin , imipenem , ceftazidime , cephalosporin , antibiotics , broth microdilution , biology , antibiotic resistance , minimum inhibitory concentration , piperacillin , bacteria , staphylococcus aureus , genetics , pseudomonas aeruginosa
MICs were determined for 218 clinical isolates of Bacteroides by a broth microdilution method. Imipenem was the most active antibiotic tested. Azlocillin, mezlocillin, and cefoxitin had comparable activities, with resistance among members of the B. fragilis group and B. capillosus. Ceftizoxime was the most active cephalosporin tested. Members of the B. fragilis group showed high levels of resistance to cefotetan and ceftazidime. Resistance to penicillin G varied from 0 to 14%.