Open AccessBioactivity of imipenem as a function of medium, time, and temperature
Author(s) -
Ellen Jo Baron,
J A Hindler
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.25.6.781
Subject(s) - imipenem , agar , microbiology and biotechnology , antibacterial agent , chemistry , biology , bacteria , antibiotics , genetics , antibiotic resistance
The bioactivity of imipenem at 20 micrograms/ml in various agar and broth media which are commonly used in susceptibility test assays was measured at different storage temperatures over time. Imipenem was found to be more stable at 4 degrees C than at -20 degrees C and least stable in all media at 35 degrees C.