Susceptibility of Gardnerella vaginalis to cephradine
Author(s) -
Ellie J. C. Goldstein,
Yung-Yuan Kwok,
Vera L. Sutter
Publication year - 1983
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.24.3.418
Subject(s) - cephradine , gardnerella vaginalis , haemophilus , serial dilution , microbiology and biotechnology , agar dilution , agar , minimum inhibitory concentration , chemistry , biology , antibiotics , bacteria , medicine , cephalosporin , bacterial vaginosis , genetics , alternative medicine , pathology
The activity of cephradine and the influence of pH on its activity against 70 Gardnerella vaginalis strains were determined. Serial dilutions of cephradine (0.062 to 256 micrograms/ml) were incorporated into Dunkelberg agar, inoculated with a Steers replicator, incubated in 5% CO2 for 48 h, and examined. The minimal inhibitory concentrations for 90% of the isolates were 16 and 8.0 micrograms/ml at pH 7.0 to 6.0 and 5.5, respectively.
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