Open AccessIn vitro susceptibility of Mycobacterium fortuitum to amoxicillin or cephalothin in combination with clavulanic acid
Author(s) -
Michael H. Cynamon,
G S Palmer
Publication year - 1983
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.23.6.935
Subject(s) - cefoxitin , clavulanic acid , mycobacterium fortuitum , amoxicillin , microbiology and biotechnology , agar dilution , cephalosporin , chemistry , biology , antibiotics , bacteria , mycobacterium , minimum inhibitory concentration , staphylococcus aureus , genetics
The comparative in vitro activity of cefoxitin, cephalothin, amoxicillin, and clavulanic acid in combination with the latter two agents against 13 isolates of Mycobacterium fortuitum was evaluated by agar dilution susceptibility testing. Amoxicillin was more active than cephalothin but less active than cefoxitin against the strains tested. Clavulanic acid in combination with these beta-lactams usually improved the activity by one or two dilutions compared with the beta-lactams alone.