Open AccessTransferable Resistance to Clindamycin, Erythromycin, and Tetracycline in Clostridium difficile
Author(s) -
J Wüst,
U Hardegger
Publication year - 1983
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.23.5.784
Subject(s) - clindamycin , tetracycline , erythromycin , microbiology and biotechnology , clostridium difficile , clostridium , antibiotics , biology , bacteria , genetics
Resistance to clindamycin, erythromycin, and streptogramins inClostridium difficile could be transferred to a susceptible strain by mixed culture at low frequencies (1 × 10−8 to 4 − 10−8 per donor cell). Transfer of tetracycline resistance occurred at frequencies of 3 × 10−7 to 5 × 10−7 . No plasmid DNA involved in these transfers could be detected.