Homogeneous enzyme immunoassay for netilmicin | Zendy

Markus R. Wenk | Zendy; R Hemmann | Zendy; Ferenc Folláth | Zendy

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Homogeneous enzyme immunoassay for netilmicin

Author(s) -

Markus R. Wenk,

R Hemmann,

Ferenc Folláth

Publication year - 1982

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.22.6.954

Subject(s) - netilmicin , immunoassay , homogeneous , chromatography , enzyme , chemistry , medicine , antibiotics , biochemistry , immunology , mathematics , gentamicin , antibody , combinatorics , tobramycin

A newly developed homogeneous enzyme immunoassay for the determination of netilmicin in serum was evaluated and compared with a radioenzymatic assay. A total of 102 serum samples from patients treated with netilmicin were measured by both methods. This comparison showed an excellent correlation (r = 0.993). The enzyme immunoassay has proved to be precise, accurate, and specific. Because of its rapidity and the ease of performance, this method is a useful alternative to current assays for monitoring serum netilmicin concentrations.

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