Open AccessHomogeneous enzyme immunoassay for netilmicin
Author(s) -
Markus R. Wenk,
R Hemmann,
Ferenc Folláth
Publication year - 1982
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.22.6.954
Subject(s) - netilmicin , immunoassay , homogeneous , chromatography , enzyme , chemistry , medicine , antibiotics , biochemistry , immunology , mathematics , gentamicin , antibody , combinatorics , tobramycin
A newly developed homogeneous enzyme immunoassay for the determination of netilmicin in serum was evaluated and compared with a radioenzymatic assay. A total of 102 serum samples from patients treated with netilmicin were measured by both methods. This comparison showed an excellent correlation (r = 0.993). The enzyme immunoassay has proved to be precise, accurate, and specific. Because of its rapidity and the ease of performance, this method is a useful alternative to current assays for monitoring serum netilmicin concentrations.