Comparative in vitro activity of cefmenoxime, cefotaxime, cefuroxime, cefoxitin, and penicillin against Neisseria gonorrhoeae | Zendy

M Y Khan | Zendy; Y Siddiqui | Zendy; Maggie Simpson | Zendy; R P Gruninger | Zendy

Open Access

Comparative in vitro activity of cefmenoxime, cefotaxime, cefuroxime, cefoxitin, and penicillin against Neisseria gonorrhoeae

Author(s) -

M Y Khan,

Y Siddiqui,

Maggie Simpson,

R P Gruninger

Publication year - 1981

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.20.5.681

Subject(s) - cefoxitin , cefotaxime , neisseria gonorrhoeae , penicillin , microbiology and biotechnology , cefuroxime , cephalosporin , antibiotics , chemistry , biology , bacteria , staphylococcus aureus , genetics

The in vitro activity of a new beta-lactam antibiotic, cefmenoxime, was compared with those of cefotaxime, cofuroxime, cefoxitin, and penicillin against 72 beta-lactamase-negative and 26 beta-lactamase-positive Neisseria gonorrhoeae. Cefmenoxime was as active as cefotaxime and more active than the other three antimicrobial agents. It inhibited all isolates, regardless of beta-lactamase activity, at a concentration of less than or equal to 0.015 microgram/ml.

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