Open AccessImmunological properties of beta-lactamases that hydrolyze cefuroxime and cefotaxime
Author(s) -
Kanji Hirai,
Kenichi Sato,
Nobuyuki Matsubara,
Ryoichi Katsumata,
Matsuhisa Inoue,
Susumu Mitsuhashi
Publication year - 1981
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.20.2.262
Subject(s) - cefotaxime , cefuroxime , proteus vulgaris , microbiology and biotechnology , proteus , pseudomonas , beta (programming language) , antiserum , cephalosporin , beta lactamase , chemistry , biology , bacteria , antibiotics , pseudomonas aeruginosa , biochemistry , antibody , immunology , escherichia coli , genetics , gene , computer science , programming language
Antiserum against purified beta-lactamase from Proteus vulgaris GN7919 cross-reacted with beta-lactamases produced by strains of Pseudomonas cepacia in a neutralization test. Anti-P. cepacia beta-lactamase serum, however, did not show any cross-reactions with P. vulgaris beta-lactamases. Each of these enzymes can hydrolyze cefuroxime and cefotaxime.