Open AccessEffect of N-formimidoyl thienamycin (MK0787) on beta-lactamases and activity against beta-lactamase-producing strains
Author(s) -
Masato Toda,
Kazuo Sato,
Hisayoshi Nakazawa,
Matsuhisa Inoue,
Susumu Mitsuhashi
Publication year - 1980
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.18.5.837
Subject(s) - thienamycin , beta (programming language) , chemistry , beta lactam , beta lactamase , microbiology and biotechnology , antibiotics , biochemistry , biology , escherichia coli , computer science , gene , programming language
N-Formimidoyl thienamycin (MK0787) was active against beta-lactamase-producing strains and was an effective inhibitor of beta-lactamases extracted and purified from these strains except for plasmid-mediated penicillinase type IV.