Open AccessAntiherpesviral activity and inhibitory action on cell growth of 5-alkenyl derivatives of 1-beta D-arabinofuranosyluracil
Author(s) -
Haruhiko Machida,
Akira Kuninaka,
Hiroshi Yoshino,
Kiyoshi Ikeda,
Yoshihisa Mizuno
Publication year - 1980
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.17.6.1030
Subject(s) - beta (programming language) , cell growth , inhibitory postsynaptic potential , chemistry , biological activity , biology , biochemistry , microbiology and biotechnology , in vitro , endocrinology , computer science , programming language
Antiherpesviral activity of 5-vinyl-1-beta-D-arabinofuranosyluracil was as high as that of 1-beta-D-arabinofuranosylthymine, whereas the former was less inhibitory to cell growth than the latter. 5-Propenyl- and 5-butenyl-1-beta-D-arabinofuranosyluracil were less active than 5-vinyl-1-beta-D-arabinofuranosyluracil.