
Activity of beta-lactamase produced by Bacteroides fragilis against newly introduced cephalosporins
Author(s) -
Kenichi Sato,
Matsuhisa Inoue,
Susumu Mitsuhashi
Publication year - 1980
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.17.4.736
Subject(s) - bacteroides fragilis , cephalosporin , cefuroxime , bacteroidaceae , microbiology and biotechnology , bacteroides , beta lactamase , chemistry , antibiotics , biology , bacteria , biochemistry , escherichia coli , genetics , gene
The purified beta-lactamase from Bacteroides fragilis hydrolyzed newly introduced cephalosporins including cefuroxime and HR 756, and was inhibited by 7 alpha-methoxylated cephalosporins such as 6059-S and YM09330.