Open AccessAssay of serum tobramycin levels with the Bactec 460
Author(s) -
L. E. Phillips,
R. Russell Martin,
Layne O. Gentry,
Thomas E. Rogers
Publication year - 1979
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.16.4.463
Subject(s) - radioimmunoassay , tobramycin , medicine , microbiology and biotechnology , chromatography , chemistry , antibiotics , pharmacology , biology , gentamicin
Serum tobramycin levels of synthetic and patient specimens were determined by the Bactec 460. The results were compared with those obtained from the same specimens by radioimmunoassay. These studies suggest that assays performed by either method should be run in duplicate or triplicate to achieve maximum accuracy. The studies also suggest that results obtained by the Bactec method are at least as reliable as those obtained by the radioimmunoassay method.