Open AccessIntegrative and Conjugative Element-Mediated Azithromycin Resistance in Multidrug-Resistant Salmonella enterica Serovar Albany
Author(s) -
Yu-Ping Hong,
Ying-Tsong Chen,
You-Wun Wang,
Bo-Han Chen,
Ru-Hsiou Teng,
Yi-Syong Chen,
Chien-Shun Chiou
Publication year - 2021
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02634-20
Subject(s) - salmonella enterica , vibrio cholerae , azithromycin , microbiology and biotechnology , serotype , multiple drug resistance , salmonella , biology , virology , antibiotic resistance , antibiotics , bacteria , genetics
We identified an erm42 -carrying integrative and conjugative element, ICE_erm42, in 26.4% of multidrug-resistant Salmonella enterica serovar Albany isolates recovered from human salmonellosis between 2014 and 2019 in Taiwan. ICE_erm42-carrying strains displayed high-level resistance to azithromycin and the element could move into the phylogenetically distant Vibrio cholerae via conjugation.