Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus | Zendy

Selvi C. Ersoy | Zendy; Henry F. Chambers | Zendy; Richard A. Proctor | Zendy; Adriana E. Rosato | Zendy; Nagendra N. Mishra | Zendy; Yan Q. Xiong | Zendy; Arnold S. Bayer | Zendy

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Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus

Author(s) -

Selvi C. Ersoy,

Henry F. Chambers,

Richard A. Proctor,

Adriana E. Rosato,

Nagendra N. Mishra,

Yan Q. Xiong,

Arnold S. Bayer

Publication year - 2021

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02621-20

Subject(s) - staphylococcus aureus , methicillin resistant staphylococcus aureus , in vivo , microbiology and biotechnology , sccmec , in vitro , gene , biology , phenotype , bacteria , biochemistry , genetics

Certain methicillin-resistant Staphylococcus aureus (MRSA) strains exhibit β-lactam susceptibility in vitro , ex vivo , and in vivo in the presence of NaHCO 3 (NaHCO 3 -responsive MRSA). Here, we investigate the impact of NaHCO 3 on factors required for PBP2a functionality.

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