Aspergillus terreus and the Interplay with Amphotericin B: from Resistance to Tolerance?
Author(s) -
Roya Vahedi-Shahandashti,
AnnaMaria Dietl,
Ulrike Binder,
Markus Nagl,
Reinhard Würzner,
Cornelia LassFlörl
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02274-21
Subject(s) - aspergillus terreus , amphotericin b , biology , microbiology and biotechnology , galleria mellonella , population , aspergillus , aspergillosis , fungicide , virulence , antifungal , immunology , medicine , genetics , botany , environmental health , gene
Aspergillus terreus is an opportunistic causative agent of invasive aspergillosis and, in most cases, it is refractory to amphotericin B (AMB) therapy. Notably, AMB-susceptibleAspergillus terreus sensu stricto (s.s.) representatives exist which are also associated with poor clinical outcomes.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom