Population Pharmacokinetics of Caspofungin and Dose Simulations in Heart Transplant Recipients | Zendy

Zheng Wu | Zendy; Jinhua Lan | Zendy; Xipei Wang | Zendy; Yijin Wu | Zendy; Fen Yao | Zendy; Yifan Wang | Zendy; Boxin Zhao | Zendy; Yirong Wang | Zendy; Jingchun Chen | Zendy; Chunbo Chen | Zendy

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Population Pharmacokinetics of Caspofungin and Dose Simulations in Heart Transplant Recipients

Author(s) -

Zheng Wu,

Jinhua Lan,

Xipei Wang,

Yijin Wu,

Fen Yao,

Yifan Wang,

Boxin Zhao,

Yirong Wang,

Jingchun Chen,

Chunbo Chen

Publication year - 2022

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.02249-21

Subject(s) - caspofungin , pharmacokinetics , volume of distribution , population , medicine , pharmacology , voriconazole , antifungal , environmental health , dermatology

The effect of heart transplantation (HTx) on the pharmacokinetics (PK) of caspofungin is not well-characterized. The aim of this study was to investigate the population PK of caspofungin in HTx and non-HTx patients and to identify covariates that may affect the PK of caspofungin.

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