Open AccessAccuracy of Direct Antimicrobial Susceptibility Testing of Gram-Negative Bacteria from Positive Blood Cultures Using MicroScan System and Value of Using Expert Rules for β-Lactam Agents
Author(s) -
Michael Jacobs,
Caryn E. Good,
Ayman M. Abdelhamed,
Robert A. Bonomo
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02148-21
Subject(s) - antimicrobial , bacteria , gram , gram positive bacteria , microbiology and biotechnology , gram negative bacteria , blood culture , categorical variable , biology , medicine , veterinary medicine , antibiotics , mathematics , statistics , escherichia coli , biochemistry , genetics , gene
Direct antimicrobial susceptibility testing (AST) of positive blood cultures with Gram-negative bacteria produces results within 24 h, compared to 48 to 96 h with conventional methods. Positive clinical blood cultures were studied, supplemented with contrived blood cultures inoculated with a spectrum of resistant isolates.