Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC β-Lactamase
Author(s) -
Magdalena A. Taracila,
Christopher R. Bethel,
Andrea M. Hujer,
Krisztina M. PappWallace,
Melissa D. Barnes,
Joseph Rutter,
Jamie VanPelt,
Ben A. Shurina,
Focco van den Akker,
Cornelius J. Clancy,
M. Hong Nguyen,
Shaoji Cheng,
Ryan K. Shields,
Richard C. Page,
Robert A. Bonomo
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02124-21
Subject(s) - ceftazidime/avibactam , meropenem , imipenem , ceftazidime , microbiology and biotechnology , avibactam , medicine , biology , chemistry , antibiotics , genetics , antibiotic resistance , pseudomonas aeruginosa , bacteria
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