Comparison of Commensal and Clinical Isolates for Diversity of Plasmids in Escherichia coli and Klebsiella pneumoniae
Author(s) -
Judith Rodríguez-Navarro,
Elisenda Miró,
Maryury Brown-Jaque,
Juan Carlos Hurtado,
ALBERT J. MORENO,
Maite Muniesa,
Juan José GonzálezLópez,
Jordi Vilà,
Paula Espinal,
Ferrán Navarro
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.02064-19
Subject(s) - plasmid , replicon , klebsiella pneumoniae , biology , microbiology and biotechnology , escherichia coli , enterobacteriaceae , genetics , gene
In this study, the plasmid content of clinical and commensal strains was analyzed and compared. The replicon profile was similar in both populations, except for L, M, A/C, and N (detected only in clinical strains) and HI1 (only in commensal strains). Although I1 and F were the most frequent replicons, only IncI1, sequence type 12 (ST12) was associated withbla CMY-2 in both populations. In contrast, the widespread resistant IncF plasmids were not linked to a single epidemic plasmid.
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