Open AccessIn Vitro Susceptibility of Gram-Negative Pathogens to Cefiderocol in Five Consecutive Annual Multinational SIDERO-WT Surveillance Studies, 2014 to 2019
Author(s) -
James A. Karlowsky,
Meredith Hackel,
Miki Takemura,
Yoshinori Yamano,
Roger Echols,
Daniel F. Sahm
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01990-21
Subject(s) - gram , microbiology and biotechnology , gram negative bacterial infections , biology , in vitro , cephalosporin , gram negative bacteria , bacteria , antibiotics , genetics , escherichia coli , gene
We reportin vitro susceptibility data from five consecutive annual SIDERO-WT surveillance studies (2014 to 2019) for cefiderocol and comparators tested against Gram-negative clinical isolates from North America and Europe. CLSI broth microdilution was used to determine MICs forEnterobacterales (n = 31,896),Pseudomonas aeruginosa (n = 7,700),Acinetobacter baumannii complex (n = 5,225),Stenotrophomonas maltophilia (n = 2,030), andBurkholderia cepacia complex (n = 425).