Open AccessTargeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya
Author(s) -
Victor Osoti,
Mercy Y. Akinyi,
Kevin Wamae,
Kelvin M. Kimenyi,
Zaydah R. de Laurent,
Leonard Ndwiga,
Paul M. Gichuki,
Collins Okoyo,
Stella Kepha,
Charles Mwandawiro,
Regina Kandie,
Philip Bejon,
Robert W. Snow,
Lynette Isabella OcholaOyier
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01945-21
Subject(s) - amplicon , deep sequencing , malaria , drug resistance , biology , amplicon sequencing , virology , medicine , computational biology , genetics , polymerase chain reaction , immunology , gene , genome , 16s ribosomal rna
Molecular surveillance ofPlasmodium falciparum parasites is important to track emerging and new mutations and trends in established mutations and should serve as an early warning system for antimalarial resistance. Dried blood spots were obtained from aPlasmodium falciparum malaria survey in school children conducted across eight counties in western Kenya in 2019.