Open AccessMatched Case-Control Study of the Long-Term Impact of Beta-Lactam Antibiotic Allergy Testing
Author(s) -
Jason A Trubiano,
Nada Marhoon,
Sara Vogrin,
Kyra Chua,
Natasha E Holmes
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01823-20
Subject(s) - antibiotics , antimicrobial stewardship , medicine , allergy , antibiotic stewardship , long term care , infection control , term (time) , intensive care medicine , immunology , antibiotic resistance , microbiology and biotechnology , biology , physics , nursing , quantum mechanics
Whereas the short-term impacts of antibiotic allergy testing on delabeling and antibiotic usage have been demonstrated, the long-term impacts have been less well defined. In a single-center matched case-control study from Melbourne, Australia, we demonstrate that a beta-lactam antibiotic allergy testing program has a significant impact on antibiotic usage and infection-related outcomes. This study supports implementation of an antibiotic allergy testing program as a standard of care of antimicrobial stewardship programs.