ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis | Zendy

Jiahui An | Zendy; Genglin Guo | Zendy; Dong Yu | Zendy; Kexin Zhu | Zendy; Chao Zhang | Zendy; Yufeng Li | Zendy

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ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis

Author(s) -

Jiahui An,

Genglin Guo,

Dong Yu,

Kexin Zhu,

Chao Zhang,

Yufeng Li

Publication year - 2020

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01716-20

Subject(s) - drug resistance , element (criminal law) , computational biology , drug , biology , microbiology and biotechnology , pharmacology , political science , law

Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in Glaesserella ( Haemophilus ) parasuis We confirmed that it could mediate the migration of antimicrobial resistance genes in G. parasuis and found that there may have been a transferring potential between different serovar strains of G. parasuis These findings demonstrate that the ICE is crucial to the horizontal transfer of antimicrobial resistance among G. parasuis strains.

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