Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis | Zendy

Ju Sang Kim | Zendy; Yong-hyun Kim | Zendy; Sang Haak Lee | Zendy; Yee Hyung Kim | Zendy; JinWoo Kim | Zendy; Ji Young Kang | Zendy; Sung Kyoung Kim | Zendy; Seung Joon Kim | Zendy; Yun-Seong Kang | Zendy; Tae-hyung Kim | Zendy; Jeongha Mok | Zendy; Min Kwang Byun | Zendy; Hye Jung Park | Zendy; Joon-Sung Joh | Zendy; Yong Bum Park | Zendy; HyeongSeok Lim | Zendy; Hongjo Choi | Zendy; Seung Heon Lee | Zendy; Hye-Jin Kim | Zendy; Jeongseong Yang | Zendy; Hyunji Kim | Zendy; Xianlin Shen | Zendy; Abdullah Alsultan | Zendy; Insook Cho | Zendy; Lawrence Geiter | Zendy; Tae Sun Shim | Zendy

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Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis

Author(s) -

Ju Sang Kim,

Yong-hyun Kim,

Sang Haak Lee,

Yee Hyung Kim,

JinWoo Kim,

Ji Young Kang,

Sung Kyoung Kim,

Seung Joon Kim,

Yun-Seong Kang,

Tae-hyung Kim,

Jeongha Mok,

Min Kwang Byun,

Hye Jung Park,

Joon-Sung Joh,

Yong Bum Park,

HyeongSeok Lim,

Hongjo Choi,

Seung Heon Lee,

Hye-Jin Kim,

Jeongseong Yang,

Hyunji Kim,

Xianlin Shen,

Abdullah Alsultan,

Insook Cho,

Lawrence Geiter,

Tae Sun Shim

Publication year - 2021

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01684-21

Subject(s) - ethambutol , medicine , pyrazinamide , isoniazid , linezolid , rifampicin , antibacterial agent , tuberculosis , gastroenterology , adverse effect , microbiology and biotechnology , antibiotics , pharmacology , bacteria , biology , staphylococcus aureus , pathology , vancomycin , genetics

Delpazolid, an oxazolidinone, has been studied in non-clinical studies of efficacy and toxicity and Phase 1 clinical studies. Delpazolid hasin vitro activity against Gram-positive bacteria, includingMycobacterium tuberculosis .

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