Open AccessScoping Review of Antimalarial Drug Candidates in Phase I and II Drug Development
Author(s) -
Azrin N Abd-Rahman,
Sophie Zaloumis,
James S. McCarthy,
Julie A. Simpson,
Robert J. Commons
Publication year - 2022
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01659-21
Subject(s) - medicine , drug , pharmacology , drug development , plasmodium falciparum , pharmacokinetics , pharmacodynamics , malaria , clinical trial , drug resistance , antimalarial agent , population , biology , immunology , environmental health , microbiology and biotechnology
The emergence and spread of parasite resistance to currently available antimalarials has highlighted the importance of developing novel antimalarials. This scoping review provides an overview of antimalarial drug candidates undergoing phase I and II studies between 1 January 2016 and 28 April 2021.