Open AccessFirst Occurrence of the OXA-198 Carbapenemase in Enterobacterales
Author(s) -
Rémy A. Bonnin,
Agnès B Jousset,
Lauraine Gauthier,
Cécile Emeraud,
Delphine Girlich,
Aimie Sauvadet,
Garance Cotellon,
Thomas Jové,
Laurent Dortet
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01471-19
Subject(s) - integron , plasmid , microbiology and biotechnology , biology , citrobacter , enterobacteriaceae , enterobacteriaceae infections , carbapenem , bacteria , gene , antibiotics , genetics , escherichia coli
A carbapenem-resistant Citrobacter sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in Enterobacterales .