First Occurrence of the OXA-198 Carbapenemase in Enterobacterales | Zendy

Rémy A. Bonnin | Zendy; Agnès B. Jousset | Zendy; Lauraine Gauthier | Zendy; Cécile Emeraud | Zendy; Delphine Girlich | Zendy; Aimie Sauvadet | Zendy; Garance Cotellon | Zendy; Thomas Jové | Zendy; Laurent Dortet | Zendy; Thierry Naas | Zendy

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First Occurrence of the OXA-198 Carbapenemase in Enterobacterales

Author(s) -

Rémy A. Bonnin,

Agnès B. Jousset,

Lauraine Gauthier,

Cécile Emeraud,

Delphine Girlich,

Aimie Sauvadet,

Garance Cotellon,

Thomas Jové,

Laurent Dortet,

Thierry Naas

Publication year - 2020

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01471-19

Subject(s) - integron , plasmid , microbiology and biotechnology , biology , citrobacter , enterobacteriaceae infections , enterobacteriaceae , carbapenem , bacteria , gene , antibiotics , genetics , escherichia coli

A carbapenem-resistant Citrobacter sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in Enterobacterales .

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