Open AccessComparative In Vitro Activities of Ceftaroline and Tedizolid against Clinical Strains of Staphylococcus aureus and Enterococcus : Results from the China Antimicrobial Surveillance Network (CHINET) in 2018
Author(s) -
Yan Guo,
Yang Yang,
Yonggui Zheng,
Wei Shi,
Daqiang Yin,
Demei Zhu,
Fupin Hu
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01461-20
Subject(s) - staphylococcus aureus , enterococcus faecalis , enterococcus faecium , antimicrobial , microbiology and biotechnology , enterococcus , medicine , biology , antibiotics , bacteria , genetics
The in vitro activities of ceftaroline and tedizolid were compared against Staphylococcus aureus , Enterococcus faecalis , and Enterococcus faecium clinical isolates collected from the China Antimicrobial Surveillance Network. Ceftaroline demonstrated potent activity against S. aureus isolates (MIC 50/90 , ≤0.25/1 mg/liter). Tedizolid was also highly active against S. aureus (MIC 50/90 , 0.25/0.5 mg/liter) and Enterococcus (MIC 50/90 , 0.5/0.5 mg/liter) isolates. Our results support the clinical usefulness of ceftaroline and tedizolid in treating Gram-positive infections.