Comparative In Vitro Activities of Ceftaroline and Tedizolid against Clinical Strains of Staphylococcus aureus and Enterococcus : Results from the China Antimicrobial Surveillance Network (CHINET) in 2018 | Zendy

Yan Guo | Zendy; Yang Yang | Zendy; Yonggui Zheng | Zendy; Shi Wu | Zendy; Dandan Yin | Zendy; Demei Zhu | Zendy; Fupin Hu | Zendy

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Comparative In Vitro Activities of Ceftaroline and Tedizolid against Clinical Strains of Staphylococcus aureus and Enterococcus : Results from the China Antimicrobial Surveillance Network (CHINET) in 2018

Author(s) -

Yan Guo,

Yang Yang,

Yonggui Zheng,

Shi Wu,

Dandan Yin,

Demei Zhu,

Fupin Hu

Publication year - 2020

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.01461-20

Subject(s) - staphylococcus aureus , enterococcus faecalis , enterococcus faecium , antimicrobial , microbiology and biotechnology , enterococcus , medicine , biology , antibiotics , bacteria , genetics

The in vitro activities of ceftaroline and tedizolid were compared against Staphylococcus aureus , Enterococcus faecalis , and Enterococcus faecium clinical isolates collected from the China Antimicrobial Surveillance Network. Ceftaroline demonstrated potent activity against S. aureus isolates (MIC 50/90 , ≤0.25/1 mg/liter). Tedizolid was also highly active against S. aureus (MIC 50/90 , 0.25/0.5 mg/liter) and Enterococcus (MIC 50/90 , 0.5/0.5 mg/liter) isolates. Our results support the clinical usefulness of ceftaroline and tedizolid in treating Gram-positive infections.

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