Open AccessPoint Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14α-Sterol Demethylase, Leads to Triazole Resistance
Author(s) -
Mariana Handelman,
Zohar Meir,
Jennifer Scott,
Yona Shadkchan,
Wei Liu,
Ronen BenAmi,
Jorge Amich,
Nir Osherov
Publication year - 2021
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01252-21
Subject(s) - aspergillus fumigatus , ergosterol , biology , microbiology and biotechnology , triazole , mutation , lanosterol , voriconazole , point mutation , posaconazole , drug resistance , aspergillus , aspergillosis , sterol , antifungal , gene , genetics , chemistry , biochemistry , immunology , organic chemistry , cholesterol
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom