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National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)
Author(s) -
PoYu Liu,
Yu-Lin Lee,
Min-Chi Lu,
PeiLan Shao,
PoLiang Lu,
YenHsu Chen,
ShuHsing Cheng,
WenChien Ko,
Chi-Ying Lin,
Ting-Shu Wu,
MuhYong Yen,
Lih-Shinn Wang,
Chang-Pan Liu,
WenSen Lee,
Yao-Shen Chen,
FuDer Wang,
Shu-Hui Tseng,
ChaoNan Lin,
Hung-Jen Tang,
YuHui Chen,
WangHuei Sheng,
Chun-Ming Lee,
Ming-Huei Liao,
PoRen Hsueh
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01089-20
Subject(s) - acinetobacter baumannii , colistin , pseudomonas aeruginosa , microbiology and biotechnology , klebsiella pneumoniae , antimicrobial , mcr 1 , antibiotic resistance , biology , acinetobacter , bacteria , escherichia coli , virology , enterobacteriaceae , medicine , antibiotics , gene , genetics
A multicenter collection of bacteremic isolates of Escherichia coli ( n = 423), Klebsiella pneumoniae ( n = 372), Pseudomonas aeruginosa ( n = 300), and Acinetobacter baumannii complex ( n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae ( n = 28) and one (20%) carbapenem-resistant E. coli ( n  = 5) isolate harbored bla KPC ( n = 17), bla OXA-48 ( n  = 2), and bla VIM ( n = 1) genes.

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