Open AccessNational Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)
Author(s) -
PoYu Liu,
Yu Lin Lee,
Min Lü,
Pei-Lan Shao,
Po Liang Lu,
Yen Hsu Chen,
Shu Hsing Cheng,
Wen Chien Ko,
Chia-Yang Lin,
Ting Wu,
Muh Yong Yen,
Lih Shinn Wang,
Chang Pan Liu,
Wen Sen Lee,
Yao Shen Chen,
Fu Der Wang,
Sheng-Hong Tseng,
Chao Lin,
Hung Jen Tang,
Yu Hui Chen,
Sheng Wang,
Chun Ming Lee,
Ming-Hui Liao,
PoRen Hsueh
Publication year - 2020
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.01089-20
Subject(s) - acinetobacter baumannii , colistin , pseudomonas aeruginosa , microbiology and biotechnology , klebsiella pneumoniae , mcr 1 , antimicrobial , antibiotic resistance , acinetobacter , biology , escherichia coli , bacteria , enterobacteriaceae , medicine , antibiotics , gene , genetics
A multicenter collection of bacteremic isolates of Escherichia coli ( n = 423), Klebsiella pneumoniae ( n = 372), Pseudomonas aeruginosa ( n = 300), and Acinetobacter baumannii complex ( n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae ( n = 28) and one (20%) carbapenem-resistant E. coli ( n = 5) isolate harbored bla KPC ( n = 17), bla OXA-48 ( n = 2), and bla VIM ( n = 1) genes.