Susceptibility Trends of Zoliflodacin against Multidrug-Resistant Neisseria gonorrhoeae Clinical Isolates in Nanjing, China, 2014 to 2018 | Zendy

Wenjing Le | Zendy; Xiaohong Su | Zendy; Xiangdi Lou | Zendy; Xuechun Li | Zendy; Xiangdong Gong | Zendy; Baoxi Wang | Zendy; Caroline A. Genco | Zendy; John P. Mueller | Zendy; Peter A. Rice | Zendy

Open Access

Susceptibility Trends of Zoliflodacin against Multidrug-Resistant Neisseria gonorrhoeae Clinical Isolates in Nanjing, China, 2014 to 2018

Author(s) -

Wenjing Le,

Xiaohong Su,

Xiangdi Lou,

Xuechun Li,

Xiangdong Gong,

Baoxi Wang,

Caroline A. Genco,

John P. Mueller,

Peter A. Rice

Publication year - 2020

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.00863-20

Subject(s) - neisseria gonorrhoeae , microbiology and biotechnology , antibiotics , multiple drug resistance , biology , neisseriaceae , china , gonorrhea , medicine , virology , geography , archaeology , human immunodeficiency virus (hiv)

Previously, we reported the potent activity of a novel spiropyrimidinetrione, zoliflodacin, against Neisseria gonorrhoeae isolates collected in 2013 from symptomatic men in Nanjing, China. Here, we investigated trends of susceptibilities to zoliflodacin in 986 isolates collected from men between 2014 and 2018. N. gonorrhoeae isolates were tested for susceptibility to zoliflodacin and seven other antibiotics.

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