Open AccessMAB_2355c Confers Macrolide Resistance in Mycobacterium abscessus by Ribosome Protection
Author(s) -
Qi Guo,
Yongjie Zhang,
Junsheng Fan,
Haonan Zhang,
Zhemin Zhang,
Bing Li,
Haiqing Chu
Publication year - 2021
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00330-21
Subject(s) - complementation , mycobacterium abscessus , biology , ribosome , microbiology and biotechnology , monoclonal antibody , mycobacterium , gene , biochemistry , mutant , genetics , rna , bacteria , antibody
Macrolide resistance is always a concern when treatingMycobacterium abscessus infections. MAB_2355c was identified previously as a possible new factor that confers the intrinsic resistance of 194 clinicalM. abscessus isolates to clarithromycin.