The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants | Zendy

Liu Cao | Zendy; Yingjun Li | Zendy; Sidi Yang | Zendy; Guanguan Li | Zendy; Qifan Zhou | Zendy; Jing Sun | Zendy; Tiefeng Xu | Zendy; Yang Yang | Zendy; Ruyan Liao | Zendy; Yongxia Shi | Zendy; Yujian Yang | Zendy; Tiaozhen Zhu | Zendy; SI-YAO HUANG | Zendy; Yanxi Ji | Zendy; Cong Feng | Zendy; Yinzhu Luo | Zendy; Yujun Zhu | Zendy; Hemi Luan | Zendy; Huan Zhang | Zendy; Jing-diao Chen | Zendy; Xue Liu | Zendy; Renru Luo | Zendy; Lihong Liu | Zendy; Ping Wang | Zendy; Yang Yu | Zendy; Fan Xing | Zendy; Bixia Ke | Zendy; Huanying Zheng | Zendy; Xiaoling Deng | Zendy; Wenyong Zhang | Zendy; Chuwen Lin | Zendy; Mǎng Shī | Zendy; Chunmei Li | Zendy; Yu Zhang | Zendy; Lu Zhang | Zendy; Jun Dai | Zendy; Hongzhou Lu | Zendy; Jincun Zhao | Zendy; Xumu Zhang | Zendy; Deyin Guo | Zendy

Open Access

The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants

Author(s) -

Liu Cao,

Yingjun Li,

Sidi Yang,

Guanguan Li,

Qifan Zhou,

Jing Sun,

Tiefeng Xu,

Yang Yang,

Ruyan Liao,

Yongxia Shi,

Yujian Yang,

Tiaozhen Zhu,

SI-YAO HUANG,

Yanxi Ji,

Cong Feng,

Yinzhu Luo,

Yujun Zhu,

Hemi Luan,

Huan Zhang,

Jing-diao Chen,

Xue Liu,

Renru Luo,

Lihong Liu,

Ping Wang,

Yang Yu,

Fan Xing,

Bixia Ke,

Huanying Zheng,

Xiaoling Deng,

Wenyong Zhang,

Chuwen Lin,

Mǎng Shī,

Chunmei Li,

Yu Zhang,

Lu Zhang,

Jun Dai,

Hongzhou Lu,

Jincun Zhao,

Xumu Zhang,

Deyin Guo

Publication year - 2022

Publication title -

science translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.abm7621

Subject(s) - prodrug , bioavailability , pharmacology , medicine , oral administration , virus , drug , potency , adenosine , in vitro , virology , chemistry , biochemistry

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