Open AccessAntisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment
Author(s) -
Tracy L. Hagemann,
Berit Powers,
NiHsuan Lin,
Ahmed F. Mohamed,
Katerina L. Dague,
Seth C. Hannah,
Gemma Bachmann,
Curt Mazur,
Frank Rigo,
Abby L. Olsen,
Mel Β. Feany,
MingDer Perng,
Robert F. Berman,
Albee Messing
Publication year - 2021
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.abg4711
Subject(s) - astrogliosis , leukodystrophy , white matter , pathology , disease , medicine , myelin , neuroscience , neuropathology , biology , central nervous system , magnetic resonance imaging , radiology
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