Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer’s disease
Author(s) -
Chae Kim,
Tracy Haldiman,
SangGyun Kang,
Lenka Hromádková,
Zhuang Zhuang Han,
Wei Chen,
Frances Lissemore,
Alan J. Lerner,
Rohan de Silva,
Mark L. Cohen,
David Westaway,
Jiri Safar
Publication year - 2022
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.abg0253
Subject(s) - conformational isomerism , disease , protein folding , population , tau protein , phenotype , biology , cognitive decline , alzheimer's disease , chemistry , microbiology and biotechnology , evolutionary biology , neuroscience , genetics , medicine , dementia , pathology , gene , molecule , environmental health , organic chemistry
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