Open AccessPantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia
Author(s) -
Chitra Subramanian,
Matthew W. Frank,
Rajendra Tangallapally,
MiKyung Yun,
Anne Edwards,
Stephen W. White,
Richard Lee,
Charles O. Rock,
Suzanne Jackowski
Publication year - 2021
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.abf5965
Subject(s) - coenzyme a , citric acid cycle , carnitine , acetylcarnitine , propionic acidemia , biochemistry , mitochondrion , alpha ketoglutarate , chemistry , metabolism , endocrinology , biology , medicine , enzyme , reductase
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