AD-linked R47H-TREM2mutation induces disease-enhancing microglial states via AKT hyperactivation | Zendy

Faten A. Sayed | Zendy; Lay Kodama | Zendy; Li Fan | Zendy; Gillian Carling | Zendy; Joe C. Udeochu | Zendy; David Le | Zendy; Qingyun Li | Zendy; Lu Zhou | Zendy; Man Ying Wong | Zendy; Rose Horowitz | Zendy; Pearly Ye | Zendy; Hansruedi Mathys | Zendy; Minghui Wang | Zendy; Xiang Niu | Zendy; Linas Mažutis | Zendy; Xueqiao Jiang | Zendy; Xueting Wang | Zendy; Fuying Gao | Zendy; Matthew Brendel | Zendy; Maria A. Telpoukhovskaia | Zendy; Tara E. Tracy | Zendy; Georgia Frost | Zendy; Yungui Zhou | Zendy; Yaqiao Li | Zendy; Yue Qiu | Zendy; Zuolin Cheng | Zendy; Guoqiang Yu | Zendy; John Hardy | Zendy; Giovanni Coppola | Zendy; Fei Wang | Zendy; Michael DeTure | Zendy; Bin Zhang | Zendy; Lei Xie | Zendy; John Q. Trajnowski | Zendy; Virginia M.Y. Lee | Zendy; Shiaoching Gong | Zendy; Subhash C. Sinha | Zendy; Dennis W. Dickson | Zendy; Wenjie Luo | Zendy; Li Gan | Zendy

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AD-linked R47H-TREM2mutation induces disease-enhancing microglial states via AKT hyperactivation

Author(s) -

Faten A. Sayed,

Lay Kodama,

Li Fan,

Gillian Carling,

Joe C. Udeochu,

David Le,

Qingyun Li,

Lu Zhou,

Man Ying Wong,

Rose Horowitz,

Pearly Ye,

Hansruedi Mathys,

Minghui Wang,

Xiang Niu,

Linas Mažutis,

Xueqiao Jiang,

Xueting Wang,

Fuying Gao,

Matthew Brendel,

Maria A. Telpoukhovskaia,

Tara E. Tracy,

Georgia Frost,

Yungui Zhou,

Yaqiao Li,

Yue Qiu,

Zuolin Cheng,

Guoqiang Yu,

John Hardy,

Giovanni Coppola,

Fei Wang,

Michael DeTure,

Bin Zhang,

Lei Xie,

John Q. Trajnowski,

Virginia M.Y. Lee,

Shiaoching Gong,

Subhash C. Sinha,

Dennis W. Dickson,

Wenjie Luo,

Li Gan

Publication year - 2021

Publication title -

science translational medicine

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.abe3947

Subject(s) - hyperactivation , protein kinase b , microglia , mutation , cancer research , disease , pi3k/akt/mtor pathway , trem2 , chemistry , microbiology and biotechnology , medicine , pharmacology , biology , genetics , immunology , signal transduction , inflammation , gene

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