Open AccessBreaking the bond between tetranectin and HMGB1 in sepsis
Author(s) -
Cameron W. Paterson,
Mandy L. Ford,
Craig M. Coopersmith
Publication year - 2020
Publication title -
science translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.abb2575
Subject(s) - hmgb1 , high mobility group , monoclonal antibody , sepsis , medicine , immunology , microbiology and biotechnology , chemistry , antibody , inflammation , biology , biochemistry , gene
The interaction between tetranectin and high-mobility group box-1 protein may be manipulated via monoclonal antibodies to improve survival in sepsis (Chen et al. same issue).
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