β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade | Zendy

Fang Zhang | Zendy; Mary Gan | Zendy; Yunjia Chen | Zendy; Shun Yan | Zendy; Sixue Zhang | Zendy; Wendy Feng | Zendy; Jiahui Tao | Zendy; Bingdong Sha | Zendy; Zhenghui Liu | Zendy; Takashi Saito | Zendy; Takaomi C. Saido | Zendy; C. Dirk Keene | Zendy; Kai Jiao | Zendy; Erik D. Roberson | Zendy; Huaxi Xu | Zendy; Qin Wang | Zendy

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β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade

Author(s) -

Fang Zhang,

Mary Gan,

Yunjia Chen,

Shun Yan,

Sixue Zhang,

Wendy Feng,

Jiahui Tao,

Bingdong Sha,

Zhenghui Liu,

Takashi Saito,

Takaomi C. Saido,

C. Dirk Keene,

Kai Jiao,

Erik D. Roberson,

Huaxi Xu,

Qin Wang

Publication year - 2020

Publication title -

science translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.aay6931

Subject(s) - norepinephrine , cascade , pathological , signal transduction , neuroscience , microbiology and biotechnology , amyloid β , amyloid (mycology) , chemistry , pathogenesis , cancer research , endocrinology , medicine , biology , pathology , disease , dopamine , chromatography

Noradrenergic signaling sensitizes pathological GSK3β/tau activation to nanomolar Aβ.

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